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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b084ab51e653d1c4994fb4d0d4a52d7eb992e49a073ece92e10dd97472be6342' 
  AND token = 'O5Me0azj2Ukvz5xR6pyJyiIge+vWzK7LBExnYeR6C10=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}