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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eee95b7cba6b047263e4ea2c474cc050705a8b25000b6e3ebbaf159ca4381564' 
  AND token = 'FmId5Nmmlh187xiAByL+1PonpoVp/i3qzG21hCXH4No=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}