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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b00e3d0b56dd855976507a30f431d68b6129e07ad2517104e74c1db2df9d87c7' 
  AND token = '+0PeoNbHtP/6ynzO0Cte9uDVlt55YqmwVD3MoiARKpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}