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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '95121640d4bb5377e47be32808f3900f4d810e7b734b6b71f6e33de339637116' 
  AND token = 'L3KddrzLCOv3M3QUBW4LTWsb6SsSTLWDTmKMEx2k0A0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}