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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25acdbd5ac9e652d4bc829f0e1ad8659b7b0201566e10a526a787148b6922a24' 
  AND token = '7mIWtlbmV0IH5F+3YPAIGFPYYqXPKYM7S800Tbv08Yo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}