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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6c78a0ad3ba64d48ed260b470ffb2c2dc0fa21155faf156fc26c11d90ef812b' 
  AND token = 'iAIoVwr9Q229j4YDLl86NK2+z0XASLlMvY9lKx4m2wo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}