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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0529a8dcfe47b242b1548d363ca97f8dae43ee9febbb3990be7e310ddd5a1301' 
  AND token = 'IHRkWbs37CxEudgJKryTi/6ttZBEqaMapC2zfgiS/p0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}