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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b52bc295ce4020d9fd82c933437646bc3cdaec360c1b0cb59e3f2612d8457f22' 
  AND token = '6Adch3sCP+9kkwLhD2Wdqc0kTFWQ4m3Q/4nEvrhEvdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}