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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3a01ad127172731d7bcbe11abae53ca459483b863bb89a23348bff66c0d0871' 
  AND token = 'vRVxyqhm8t0diTZTZB0s5lfYYMlq4rpgrz0LPeXtl18=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}