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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89b797213ec471375cc7cae8c2a0908e0a1835cb106c140dd3a15dbaef4143a0' 
  AND token = '6w/IemPZgAOII7cB3hgjbo4FD+ejhd3rPvY8vJ2dh2s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}