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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9af579ea0163dab298abf90d1b7349fcb789eb5b275068f655e0e688fe76b963' 
  AND token = '2qQ7wivvVyfyOb8oFqM3zrCZRZXKqP8DFCHcSt6/K48=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}