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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a970ca3729a42871d8b1d450fe3bb1554d1889cb61d64786b0fac015ea655f6' 
  AND token = 'Lsz+AoXtA+dE8BycQMPmLh9BPQ3N7Gx3dKvSLgCLb3A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}