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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d60d6205ea9264e512a5c281e7a906b4d9521d197341a7818983a3f43d20859' 
  AND token = 'oxS3OMyYS9jnKx3HiRmkoL+8UMEYWNX/khbVmOUHArQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}