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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7165cf641de769b0dce45b2217aa5718f200ac7ba85255b86aff330d16420493' 
  AND token = 'zqhBX1y27AxSsy1IvFkG+5XbAAmo+Z33uRQaqLyoiOg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}