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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '127c87b4a18c2fc5cd2f70179ae4c518f25c9f23aa537720488d01177261a515' 
  AND token = 'mgmi+UN1QXz2PKTzTXXzBbyyvrVrGV6t/JmfpkIPQNE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}