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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c8a8bbd50760d6722d4c95b6651644efcf9a555096d3e122f2eb7edea3662697' 
  AND token = 'M1g0lwa51EWBjkHObYv87A+p7SNUbQT7JFDm6H9IkL0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}