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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '41fdf7433638387b17e3749f7eec724b83b62c17cbef88e110e0091c3b8fe50f' 
  AND token = '0F+5UJtFCM4PfrNPTPMTFYcP1TF+E/IxHKT0G9iUxZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}