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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e44d87769d4a1086ba2d072672cf8a1a3a0c88682a78f8470fa109835b9b934' 
  AND token = '+ss5X1YUEwe5AU1oWJfFBVpCEOc+lLEsQba0qyA5gZI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}