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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4b148e0154721c5720698504405ae0ee8ef1d15c12f6b54616d657bad1cf8963' 
  AND token = 't2lBGl75o7OFjKsSWIiq4P0LYuz5L+khW+5T3NpdTaw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}