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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdf7fe74de1e0d7a98c93f1f3fedfc59083248dd692be0451521f10aaccadfd0' 
  AND token = 't3VddzVkWaMpOeSZc02+gwVhc73vtXUluij02eThnMU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}