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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b3f9febe4752ddff0b0bd151755e45a4d5de6b8c663971de074ae4b1dda2f083' 
  AND token = 'M5OHE+H81Me05nx3DFU9qsZYBi6jnEVQVzcNp6PW90E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}