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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9444eec165bb657486855f4620f415ec655845c8ab3b2935a73ad1cbc25b00cb' 
  AND token = 'RDvWot5VoPofm0M1PWY21eRShUBnpSrmM/IVArrxw38=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}