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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fdce1fc7849c3f9030a85b4dd261aedb20189b2dbb422b33ed8a3c40180634b6' 
  AND token = 'p1C1N6ODJEWUbG/Zq3zKaex0lAdSW5qgk5sz5OKcr78=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}