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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca12b3cb67a620ab51beae7cfc9ee88c4418e5a2c8f260200cb8d790125dc56a' 
  AND token = 'IpPTJZY4Tk9TIVMRGndKDWjtnx628dQMWMEqSTz+NNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}