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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a45fbe3cc431f709e01df836ca34ab3786556a08c4fa78aa8be1940b04efdc6' 
  AND token = 'cI5GZhqBRXIFY7m29PR6e597b8BvXLQcRw9q/9XvBsA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}