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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7259eaa4660244c303e3de6866c3ef19f51c8f035cc14555ca15d48d67d5e5c0' 
  AND token = 'XVsBDIAhR373oTtqm5bzI5Hfin0s9jnd5ngswtMxIYQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}