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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c8f718d34470c96a53effac97a1a66daedb0eb5013af8fcb6e0da47fbc9906b' 
  AND token = '7TcCOLAD2Y8xgmyp03HM78++uamn3HIK1Z9H9M33PXQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}