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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1e4040d35029ed80d63df986d0e9de076393c10cd6373ffd178a69fee43fb3d3' 
  AND token = 'FUe2eQsfgTqvq1u0Xc8k7308GwBa0JacEP3tysmAtQE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}