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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8cffd047165dde888f4adb6e3e68196e82a4f8d9e4819d462c0538be2ee28f2c' 
  AND token = 'jBeQAl1b+g7GXpGQX1kHKSIbgsygGwDYWtBs21uG4E8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}