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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a42260726fed8265495f1a120e992c9c6dd1bfb798b643b94dadf30670d7e0e' 
  AND token = 'xmxs8KyKX+5i+aKMAbFDd6L1TeILivEKQJ0Uci5dq5Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}