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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4073114fc08e9b3d736d0da9685dfc6579fb967153e5ae6785e10059e2af0066' 
  AND token = 'Mb5oG5nEVjRgfwtDtEb5Ig1S8zu2U64/5qlrgTfVj8k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}