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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '672b9a4f4f2c6914258957b5c510349ec9a9837494af6ed1e3206ac13d654384' 
  AND token = 'fqakxfk462bYhmjMWagaWUt+nD2GSTRUnf0B8gbM7S4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}