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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'afa3988c7984b8983068cc92d53c442fa519dbf5e69842c64ca7111508ad2a8f' 
  AND token = 'S0IrFIze1TG9Qy9oIsNdrjHlYDwySd6WNebwk4ZR9g4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}