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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fff4f6524e49f68853287a27d9d0fa5ca72a2a8d6fdcaf11071443f7c89f8565' 
  AND token = 'VCEZMXP6Pvde1RNaj4xqHQNqP4v38xuK4Vcgz1kXOPs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}