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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8deb133bfc8239a0f0c841c7b1e48267d4310b7b842c77a4861a8a12a71798c4' 
  AND token = 'ebH3jpZRL1+K2MJAVnM0DNv0M0A1y8YFSkCkOhz7HAk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}