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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5332bb9003556bdc2bff12b4ef360fb538d8e6e249ce3ea6586d0faaac9e1d81' 
  AND token = '7BXFBHkR756EEroo6dNekg4mlrdfXGiezshPYdGCRGc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}