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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '37a0cd35d45e64da14ea1ef6438f7768c557f15b114148cb88360d975790a135' 
  AND token = 'SpX8wPFSOt485raMb1Ebr1zWfwF9Z8uvwMIhVIsVnx4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}