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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4215d70bbcd37931a4074a172537ccb1a1bd453c077c9c5ce6f3622b250eb6e' 
  AND token = 'EkYDOIDqKXWno+hPuLMbnEIzRjNm6QH9NK5MKcO/eqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}