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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7220b50f21c33cbb338d80446f317eeba7940b554efbb7ff33e452592cbdc9f6' 
  AND token = 'ybu/0J8ZB7ztf8nh33uuw1axs5RJh3c67s0zZiG3BwM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}