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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '317049605f135a34a0fd95001011c7eb1bb607d95311c58a7c192ce986e86a94' 
  AND token = 'z3YQGp644MNxXgF/fTZ1IFlZZ4ADWT5ei86CrcuZP8Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}