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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2e0052a327b428caa8e03a6c1a231fda634f4206fcd42861d2dc471ab26a525a' 
  AND token = 'mF7uQZ+qcmSkzuOaRPF/NT1R+ZQWJTOR9Iatrp1PAgI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}