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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cb77b3b99b9069938f5e9a55c849fa80b2205cfc25118f14cade31dc6f683fd3' 
  AND token = 'fa1hxd9iOriGRsl0gfKjKZJXMGZ2X5SFcdTci7tM7G4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}