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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3c2360091dcb17031b8fbf07250bee2217a5c20cca1ef46f1973116814f6f436' 
  AND token = '2tJ+Wf73W+ckWTubNiRGiTQ37nwEhL7OIa3GEtDlw3Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}