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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49f70cc0e74c85e2c6b87b3c543356bee46a6c18e61f03dfdf440791cfc17ce0' 
  AND token = 'HfMs53UJ+qpCT3B+wdlvcRCPAr4skIpAGhscRM5v10g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}