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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '96bc8408b897d4856f7bf5d9f1619a0a59ce139a0b83dba4ee956212a159f253' 
  AND token = 'E+KLIYJsvEZKuYmY14zAesEqxEO7/0YxPOZ5Ny6DZZU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}