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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9f31b93dafd49f9c45e28619aaa2ba8736331700b2c72ed9d904f6d4e4a8cd64' 
  AND token = '5NlM/BNaN3WngVpI6FaTt2UXAsW3G4LcaZqQB7NDX8s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}