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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '12a5c73e651fb1ca5b608f33505096649af633673687ffa339ddbec0b8c8f96f' 
  AND token = 'qq0GNai4ZVx9hbpTkVp9i54I5DO5BV//gZnf/li6Leo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}