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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b12bf051d05b35f811355cb9f2e2c4fffdff3b960a26d82a2a30690d48bc68e0' 
  AND token = 'FDMk2B+TS1sbaDaDEhEDKTpa+5O/aXkcu+SJEC3r2v4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}