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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a66c48250db3fe514476c67ac0f897b2a7e12a750f45f95110dd5fd0ba7c81f5' 
  AND token = 'ygWt/1u7DKmwpS2QCd2/UCRKjFaDhFQa85GNJ1ORXTk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}