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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b3b1bd1b1bdf9856ad4070944411daff545cc98f2772cc01b4cf11c33fd41db' 
  AND token = 'nvrvZM017TDSgzEFpgrtHWvLzRZ1ivtGa2K7R8kmHQI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}